Nootropics/Coluracetam/sunifiram/unifiram//theanine/PRL-8-53/tianeptine sulfate

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric 

modulator of AMPA receptors, and has nootropic effects in animal studies with significantly

 higher potency thanpiracetam. A number of related compounds are known, the best known 

being unifiram (DM-232)

This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. 

Sunifiram improves 

cognitive deficits via CaM kinase II andprotein kinase C activation

Product Name:Sunifiram (DM-235)

Synonym:1-benzoyl-4-propanoylpiperazine

Molecular Formul

246.304 :C14H18N2O2

Molecular Weight:246.304

CAS No.:314728-85-3

Purity 99.8%

Melting point 94.5°C-95.5°C

Appearance Off-white to white crystalline powder 

Function

1.Sunifiram activates AMPA-mediated neurotransmission. 

2.Enhancing LTP in a bell-shaped dose–response relationship.  

3.Sunifiram aids in the release of acetylcholine in the cerebral cortex

OTHERS nootropics:

NSI-189/NSI-189 phosphate cas 1270138-40-3

IDRA-21  cas 22503-72-6

prl-8-53 cas 51352-87-5

Alpha-GPC  cas 28319-77-9

Aniracetam cas 72432-10-1

Coluracetam cas 135463-81-9

CDP-choline cas 987-78-0

Phenylpiracetam  cas 7458-01-7

Gaba  cas 56-12-2

L-theanine cas 3081-61-6

Nefiracetam cas 77191-36-7

Noopept   cas 157115-85-0

Oxiracetam cas 62613-82-5

Phenibut cas 1078-21-3

Pramiracetam cas 68497-62-1

Sunifiram cas 314728-85-3

Unifiram cas 272786-64-8

Amfonelic acid 

Nicotinamide ribose

Beta nicotinamide mononucletide

Tirasemitiv cas 1005491-05-3

Vinpocetine  cas 42971-09-5

Packaging Details: 25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside Delivery Detail: within 3 days when get the payment

Xi'an sgonek biological Technology Co., Ltd., was established in July 2008. It is a professional animal and plant extracts modern and advanced enterprise object, pharmaceutical intermediates, and natural active ingredients. In the development, production and marketing, is very powerful.  Headquartered in Xi'an. It has a research and development center and the Analysis and Testing Center, with strong comprehensive national strength. The company has 200 acres of experimental field of plant cultivation, extraction, distillation, rectification, chromatography, three specialized production lines, as well as 10,000 square meters of GMP standard workshop. A variety of production equipment more than 200 sets of experiments. US company to introduce the company WATERS LC-MS chromatograph and a 8453 UV-Vis spectrophotometer and Switzerland TLC scanner (HPTLC) and other advanced detection equipment to ensure the quality of our products are oriented to international standards.   Advanced equipment and professional and technical personnel, we are standing in front of the industry foundation, we thought to provide quality products and services to target customers around the word .  

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