- DALIAN HANDOM CHEMICALS CO.,LTD.
- China Manufacturer with main products:Carbomer 940 ,Carbomer 974P ,Vegan Vitamin D3 ,Sodium Hyaluronate ,Pumpkin Seed Protein ,Brown Rice Protein ,Rice Protein ,Sunflower Seed Protein ,Mung Bean Protein ,Walnut Protein ,Algae DHA powder ,Riboflavin Sodium Phosphate ,D-Alpha Tocopherol ,Folic Acid
- USD $3.00 - $12.00 / Gram |Get Latest Price
- 10 Gram / Grams
- 1000 Kilogram / Kilograms per Month
- Shanghai, Guangzhou, Beijing or Dalian
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- 7 days
|Brand Name:||HDC CHEM||Place of Origin:||China||Model Number:||HDC-VB12-002|
|Type:||Vitamins, Amino Acids and Coenzymes||Purity:||98.5%-101.0%||EINECS No.:||236-535-3|
|MF:||C63H90CoN13O14P||Other Names:||Methylcobalamin||CAS No.:||13422-55-4|
|Grade Standard:||Food Grade, Medicine Grade|
100g/tin or 1kg/tin, carton box outside.
1. Product Name: Mecobalamin
2. Alias: Algobaz; MECOBALAMIN; Vitamin B12;
MECOBALAMINE; Methylcobalamin; METHYLCOBALAMIN;
Methyl Vitamin B12; cobalt-methylcobalamin;
3. CAS No.: 13422-55-4
4. EINECS No.: 236-535-3
5. Molecular Formula: C63H91CoN13O14P
6. Molecular Weight: 1344.40
7. Chemical Structural Formula:
Vitamin B12 is a general term for vitamin B group chemicals with a cobalt ring structure. There are four types of vitamin B12 family: cyanocobalamin, hydroxocobalamin, adenosylcobalamin and methylcobalamin, but clinically used vitamin B12 usually refers to cyanocobalamin.
Cyanocobalamin and hydroxocobalamin have no direct biological activity. Cyanocobalamin is a prodrug, which can be converted into methylcobalamin and adenosylcobalamin in the human body. Methylcobalamin and adenosylcobalamin are the two active coenzyme forms of vitamin B12 in the human body.
Cyanocobalamin and hydroxocobalamin are dark red crystals or crystalline powder; adenosylcobalamin is yellow-orange hexagonal crystals, which turn dark red when exposed to air; methylcobalamin is bright red needle-like crystals or crystalline powder.
All four injections of cobalamin are red. In the storage of ordinary medicines, it is necessary to keep them away from sunlight. Cyanocobalamin is the most stable one, and generally it will not be degraded by sunlight; adenosylcobalamin and methylcobalamin are unstable when exposed to sunlight, and must be strictly protected from sunlight, and the injection time must also be shortened.
The four cobalamins can prevent and treat red blood cell anemia and treat peripheral neuropathy. In the human body, we can only use adenosylcobalamin and methylcobalamin directly, cyanocobalamin and hydroxocobalamin need to be converted into adenosylcobalamin and methylcobalamin by the organelles in the liver before they can be utilized by the human body. For people with liver diseases, such as hepatitis and cirrhosis, adenosylcobalamin and methylcobalamin should be directly supplemented to reduce the burden on the liver, and patients with liver function impairment can be given priority.
Physical & Chemical Properties:
|Solubility||Slightly soluble in DMSO and water, sparingly soluble in Methanol|
|Acid Coefficient||Pk1:7.64(+1) (25℃)|
Application of Mecobalamin:
Mecobalamin is used to treat nervous system diseases, relieve pain and numbness, quickly relieve neuralgia, improve pain caused by cervical spondylosis, and treat sudden deafness, etc.
|Test Items||Specifications||Test Methods|
|Appearance||Dark red crystals or crystalline powder||JP Monograph|
1) UV: Compare the spectrum with the reference spectrum, both spectra exhibit similar intensities of absorption at the same wavelengths.
2) Cobalt: Meets JP requirement
JP Monograph/JP <2.24>
|Clarity and color of solution||The solution is clear and red color|
1) Each area of the peaks other than mecobalamin is not more than 0.5% of the peak area of mecobalamin;
2) The total area of the peaks other than mecobalamin is not more than 2.0%
JP Monograph/JP <2.01>
|Water||≤11.5%||JP Monograph/JP <2.48>|
|Assay(on the anhydrous basis)||98.5%-101.0%||JP Monograph|
|The total aerobic microbial count||≤1000cfu/g||ChP 2020 <1105>|
|The total combined yeasts/mould count||≤100cfu/g||ChP 2020 <1105>|
Package: 100g/tin or 1kg/tin, carton box outside.
Storage Conditions: Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.
Shelf Life: 36 months under above conditions.
- DALIAN HANDOM CHEMICALS CO.,LTD.
- ContactJohn Wang
- AddressGanjingzi Dist Dalian,Liaoning
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